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OMIM is based on the published peer-reviewed biomedical literature and is used by overlapping and diverse sildenafil citrate tablets of clinicians, molecular sildenafil citrate tablets and genome scientists, as well as by students and teachers of these disciplines. Genes and phenotypes are described in separate entries and are given unique, sildenafil citrate tablets six-digit identifiers (MIM numbers).

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Phenotypic series have been created to facilitate viewing genetic heterogeneity of phenotypes. Clinical synopsis features are enhanced with UMLS, Human Phenotype Ontology and Elements of Morphology terms and image links. All OMIM data are available for FTP download and through an API.

MIMmatch is a novel outreach feature to disseminate updates and encourage collaboration. Published by Oxford University Press on behalf of Nucleic Acids Research. OMIM's task of cataloging the association between human phenotypes and their causative genes (the Morbid Map of the Genome) and classifying and naming newly recognized disorders is growing rapidly.

Establishing the relationship between genotype and phenotype has become increasingly complex. New technologies such as sildenafil citrate tablets association studies (GWAS) and array comparative genomic hybridization (aCGH) define "risk alleles" that are inherently prone to substantial interpretation and modification.

In addition, whole exome and genome sequencing are expected to result in many sildenafil citrate tablets of new mendelian disorders and their causative sildenafil citrate tablets. In preparation for the onslaught of new information, we have sildenafil citrate tablets a new Website to allow a more comprehensive and structured view of the contents of OMIM and to improve interconnectivity with complementary clinical and basic science genetics resources.

The content of OMIM is derived exclusively from the published biomedical literature and is updated daily. It currently contains 18,961 full-text entries describing phenotypes and genes. To date, 2239 genes have mutations causing disease, and 3770 diseases have a molecular basis. Approximately 70 new entries are added and 700 entries are updated sildenafil citrate tablets month. OMIM is expanding content and organization in response to shifting biological paradigms and advancing sildenafil citrate tablets. Online Mendelian Inheritance in Man (OMIM) is a comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

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